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Bernardo Miguel-Lillo Selected Research

elisidepsin

4/2016Phase Ib/II study of elisidepsin in metastatic or advanced gastroesophageal cancer (IMAGE trial).
2/2016Phase I, dose-escalating study of elisidepsin (Irvalec(®)), a plasma membrane-disrupting marine antitumor agent, in combination with erlotinib in patients with advanced malignant solid tumors.
8/2015First-in-human, phase I study of elisidepsin (PM02734) administered as a 30-min or as a 3-hour intravenous infusion every three weeks in patients with advanced solid tumors.
6/2014Phase I study of elisidepsin (Irvalec®) in combination with carboplatin or gemcitabine in patients with advanced malignancies.

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Bernardo Miguel-Lillo Research Topics

Disease

9Neoplasms (Cancer)
04/2016 - 06/2009
4Neoplasm Metastasis (Metastasis)
08/2015 - 06/2009
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2018
1Stomach Neoplasms (Stomach Cancer)
04/2016
1Exanthema (Rash)
02/2016
1Diarrhea
02/2016
1Pruritus (Itching)
02/2016
1Body Weight (Weight, Body)
08/2015
1Neutropenia
11/2012
1Hypokalemia
01/2011
1Cardiotoxicity
01/2011
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2011
1Myalgia
01/2011

Drug/Important Bio-Agent (IBA)

4elisidepsinIBA
04/2016 - 06/2014
4Proteins (Proteins, Gene)FDA Link
08/2015 - 06/2009
3Alanine Transaminase (SGPT)IBA
08/2015 - 06/2009
3Alkaline PhosphataseIBA
08/2015 - 06/2009
3Aspartate Aminotransferases (Aspartate Transaminase)IBA
08/2015 - 06/2009
3BilirubinIBA
08/2015 - 06/2009
3CreatinineIBA
08/2015 - 06/2009
2Serum AlbuminIBA
08/2015 - 11/2012
2PM 00104IBA
11/2012 - 01/2012
2Hemoglobins (Hemoglobin)IBA
01/2012 - 01/2011
2AlbuminsIBA
01/2012 - 06/2009
2plitidepsin (aplidine)IBA
01/2011 - 06/2009
1Biosimilar PharmaceuticalsIBA
01/2018
1Rituximab (Mabthera)FDA Link
01/2018
1Erlotinib Hydrochloride (CP 358,774)FDA Link
02/2016
1Transaminases (Aminotransferases)IBA
02/2016
1Antineoplastic Agents (Antineoplastics)IBA
02/2016
1kahalalide FIBA
08/2015
1Pharmaceutical PreparationsIBA
08/2015
1GemcitabineFDA Link
06/2014
1Carboplatin (JM8)FDA LinkGeneric
06/2014
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2012
1DepsipeptidesIBA
01/2011
1Cytochrome P-450 CYP3AIBA
06/2009

Therapy/Procedure

2Drug Therapy (Chemotherapy)
04/2016 - 11/2012
2Intravenous Infusions
08/2015 - 11/2012
1VAP-cyclo protocol
01/2018